How to Make Irresistible Roasted Garlic Butternut Squash Lasagna Roll-Ups

Elevate your dinner with Roasted Garlic Butternut Squash Lasagna Roll-Ups—a lighter, flavorful twist on classic lasagna. Sweet roasted butternut squash, aromatic garlic, creamy ricotta, and gooey mozzarella come together in tender noodles for a dish that’s both comforting and elegant. Free from pork, salami, wine, bacon, beer, cognac, champagne, vodka, or rum, this recipe is family-friendly, nutritious, and visually stunning. Perfect for weeknights or special occasions, each roll-up delivers creamy, savory, and slightly sweet flavors that everyone will love.

Why You’ll Love This Butternut Squash Lasagna Roll-Ups

These roll-ups are a flavor-packed, visually impressive twist on traditional lasagna. Sweet squash and roasted garlic pair perfectly with creamy cheese for a rich, satisfying bite. They’re versatile—vegetarian-friendly, easy to prep ahead, and perfect for leftovers. Portion-controlled and golden-baked, they look as good as they taste, making them ideal for dinners, gatherings, or anytime you want comfort food with a fresh, wholesome twist.

What You’ll Need

To make Roasted Garlic Butternut Squash Lasagna Roll-Ups, you’ll need simple, wholesome ingredients that pack maximum flavor:

• 9–12 lasagna noodles (uncooked or pre-cooked)
• 1 medium butternut squash (about 2 lbs), peeled and cubed
• 4–5 garlic cloves, roasted
• 1 ½ cups ricotta cheese
• 1 cup shredded mozzarella cheese, plus extra for topping
• ¼ cup grated Parmesan cheese
• 1 teaspoon dried sage or thyme
• 1 tablespoon olive oil
• Salt and pepper, to taste
• Optional: fresh parsley for garnish

Everything is easy to find at your local grocery store, and the recipe is fully vegetarian and free from any alcohol or pork products.

How to Make Butternut Squash Lasagna Roll-Ups

1. Roast the squash and garlic: Preheat oven to 400°F (200°C). Toss cubed butternut squash and garlic cloves with olive oil, salt, and pepper. Spread on a baking sheet and roast 25–30 minutes until tender.
2. Prepare filling: Mash the roasted squash and garlic, then mix with ricotta, 1 cup mozzarella, Parmesan, and dried sage. Season to taste.
3. Cook noodles: Boil lasagna noodles according to package instructions. Drain and lay flat on a clean surface.
4. Assemble roll-ups: Spread filling evenly over each noodle, then roll tightly. Place seam-side down in a greased baking dish.
5. Top and bake: Sprinkle remaining mozzarella on top. Bake at 375°F (190°C) for 20–25 minutes until cheese is melted and bubbly. Garnish with parsley before serving.

You Must Know

Roasting the garlic with the squash is essential for deep, rich flavor. Use firm butternut squash and slightly undercook noodles to prevent sogginess. Season well with salt, pepper, and herbs like sage or thyme. You can prep roll-ups ahead of time or freeze them for later—just adjust baking time if frozen.

Perfecting the Cooking Process

Spread filling evenly and roll noodles gently but firmly, placing seam-side down. Roast squash and garlic until tender and slightly caramelized. Top with mozzarella and Parmesan for a bubbly finish. Cover with foil if cheese browns too fast, and let roll-ups rest 5–10 minutes before serving for perfect texture.

Add Your Touch Butternut Squash Lasagna Roll-Ups

Make these roll-ups your own! Add sautéed spinach, kale, or mushrooms to the filling for extra nutrition and flavor. Sprinkle red pepper flakes for a mild kick, or drizzle a little balsamic glaze on top for sweetness. Fresh herbs like basil or parsley brighten the dish and make it look restaurant-ready.

Storing & Reheating

One-pot wonders you’ll crave

Store leftovers in an airtight container in the fridge for up to 3 days. To reheat, cover with foil and bake at 350°F (175°C) for 15–20 minutes until warmed through. For freezing, wrap individually or in a baking dish; bake from frozen at 375°F (190°C) for 30–35 minutes.

Chef’s Helpful Tips for Butternut Squash Lasagna Roll-Ups

Comfort food made simple

• Roast squash and garlic in a single layer for even cooking.
• Slightly undercook noodles to prevent soggy roll-ups.
• Let baked roll-ups rest 5–10 minutes before serving for easier slicing.
• Mix cheeses for a gooey, golden topping without overloading.

FAQ for Butternut Squash Lasagna Roll-Ups

Try this easy weeknight favorite

Can I make this vegan? Swap ricotta and mozzarella for plant-based alternatives.
Can I use frozen squash? Yes, just roast longer until tender.
Can I prep ahead? Absolutely—assemble and refrigerate up to a few hours before baking.
How do I prevent noodles from sticking? Lightly oil or use nonstick spray on the baking dish.

Conclusion

These Roasted Garlic Butternut Squash Lasagna Roll-Ups are a delicious twist on a classic comfort food. Sweet roasted squash, caramelized garlic, and creamy cheese wrapped in tender noodles make a dish that’s flavorful, wholesome, and visually stunning. Perfect for weeknight dinners, meal prep, or special occasions, they’re easy to customize, freezer-friendly, and sure to impress.